Determine the effects of loss of function or gain of function mutations of regulating enzymes or metabolic enzymes on the rate of a reaction given a schematic of enzyme regulation.

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Prerequiste Learning Outcomes

What the student is assumed to know before learning this outcome.

Explain how enzymes can increase the rates of biochemical reactions at the molecular level, and how they may be inhibited or regulated by drugs and toxins. [BIOC 1040] [BIOC 2300]

Why do I need to know that?

These are the student learning outcome(s) that directly require this student learning outcome.

Identify uniform and differential binding from site-directed mutagenesis studies or substrate mutilation studies to discern the role of residues in transition state and ground state binding. [BIOC 4701]
Understand loss of function versus gain of function mutations. [BIOC 4305]

Courses Covering This Learning Outcome

BIOC 2300

Determine the effects of loss of function or gain of function mutations of regulating enzymes or metabolic enzymes on the rate of a reaction given a schematic of enzyme regulation.

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