Current Crosslistings BIOC 5700
BIOC 5700
BIOC 3700
Present your experimental results to other members of the lab. [BIOC 3620] Use the scientific literature and other available resources to research topics in human biochemistry and, in a small group tutorial setting, to answer guided questions and attain learning objectives. [BIOC 1040] Acquire skills in reading and interpreting the primary scientific literature. [BIOC 4404] Understand the principles of bioenergetics, including the implications of free energy change occurring in a chemical reaction. [BIOC 2300] Describe and interrelate the hierarchical levels of protein structure (1˚ to 4˚) and provide examples of how this structure relates to the function (or dysfunction) of various classes of proteins. [BIOC 1040] [BIOC 2300] Apply peptide bond properties and hydrogen-bonding to predict primary and secondary structuring preferences. [BIOC 3700]
Assimilate and integrate the knowledge in a developing field of protein science to deliver a presentation or formulate a literate essay.Calculate association constants, given tables or graphs of raw data from experiments.Choose and explain a suitable method to analyze the binding interaction of proteins with small molecules or between proteins.Develop a knowledge of the subtleties of amino acid function within the whole protein context. (Post-translation modifications of side chains).Develop an appreciation of particular techniques in protein science that are unavailable to students in the context of Dalhousie undergraduate program.Discuss the necessity of protein turnover within cells and organisms and the degradative and regulatory mechanisms that govern protein turnover.Formulate a literate essay.Identify how post-translational modifications modulate the biophysical and the chemical properties of amino acid side chains to expand the functionality of proteins, particularly enzymes.Recall principles of redox equivalent transfers within respiratory chains.Deliver an effective oral presentation.Analyze the detailed mechanism for the generation of the proton motive force across bioenergetic membranes.Organize an effective literature search and apply it to a presentation or an essay.Understand the established principles of protein folding.Design a protein engineering experiment to answer questions about structure/function relationships in new protein.Explain the biophysics of the non-covalent forces and kinetics and mechanisms governing protein folding and stability.Apply the principles underlying structure and folding of simple soluble proteins to the more complex physical environment in which membrane proteins operate.
