Current Crosslistings BIOC 5404
BIOC 5404
BIOC 3400
Use the scientific literature and other available resources to research topics in human biochemistry and, in a small group tutorial setting, to answer guided questions and attain learning objectives. [BIOC 1040] Recall DNA replication, transcription, and RNA processing. [BIOC 4403] Explain the steps of protein synthesis identifying the differences between prokaryotes and eukaryotes. [BIOC 3400] Distinguish the nucleotides that compose DNA and RNA. [BIOC 3400] Distinguish the differences between prokaryotes and eukaryotes in terms of genome organization, gene structure, and expression and DNA replication. [BIOC 3400] Interpret roles of alternative RNA splicing in expansion of the proteome. [BIOC 4403] Understand chromatin remodelling. [BIOC 4305]
Distinguish between cis and trans regulation.Distinguish between gene activation and gene repression.Explain regulation exerted by different mechanisms of translational control.Specify methods to investigate gene regulation.Acquire skills in reading and interpreting the primary scientific literature.Identify the different types of protein factors regulating bacterial gene expression.Classify different regulatory mechanisms of gene transcription.Explain regulation by mRNA structure and stability.Identify the effects of mRNA localization on the consequences and regulation of gene expression.Identify the different types of DNA and RNA sequence elements regulating eukaryotic gene expression.Identify the different types of protein factors regulating eukaryotic gene expression.Explain how different types of DNA and RNA sequence elements are involved regulating eukaryotic gene expression.Recognize the implications of differential RNA splicing.Describe the challenges and opportunities for gene regulation offered by chromatin structure.Distinguish among various mechanisms for the modulation of chromatin effects.