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B. Sc. Biochemistry & Molecular Biology
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#cell
Describe the basic principles of intracellular signal transduction and discuss how these processes may alter gene expression, protein function and cellular fate.
[
multiple courses
]
Discuss the necessity of protein turnover within cells and organisms and the degradative and regulatory mechanisms that govern protein turnover.
[
BIOC 4700
]
Explain how protein tagging techniques can be used to determine protein localization or protein interactions in living cells or to affinity-purify proteins from cells.
[
BIOC 4501
]
Recognize GTPases as on/off switches in vesicular transport and cellular signaling.
[
BIOC 3300
]
Understand the concept of apoptosis.
[
BIOC 4305
]
Distinguish the regulators of cell cycle.
[
BIOC 4305
]
Explain cellular pathways for protein transport and modification and their effects on protein function.
[
BIOC 3300
]
Distinguish between normal and abnormal cell signalling.
[
BIOC 4305
]
Explain the steps of protein synthesis identifying the differences between prokaryotes and eukaryotes.
[
BIOC 3400
]
Understand the phases of cell cycle.
[
BIOC 4305
]
Understand cell migration.
[
BIOC 4305
]
Distinguish between cell migration and metastasis.
[
BIOC 4305
]
Explain the molecular basis of procedures such as gene cloning, cDNA and genomic DNA library screening, polymerase chain reaction (PCR) amplification of DNA, DNA sequencing, microarray technology, nuclear transfer somatic cell and induced pluripotent stem cell cloning, gene therapy.
[
BIOC 4501
]
Interpret data obtained from electrophoresis based methods (eg blotting, restriction enzyme, PFGE, gel mobility assays and CHIP).
[
BIOC 3400
]
Analyze data obtained from molecular biology procedures and explain problems associated with expression of human protein products in bacteria or other host cell systems.
[
BIOC 4501
]
Classify pathways for protein catabolism and their roles in cell biology and metabolism.
[
BIOC 3300
]
Describe cellular mechanisms of transport that enable the cell to maintain membrane asymmetry and the cellular distribution of lipids.
[
BIOC 3300
]
Distinguish the differences between prokaryotes and eukaryotes in terms of genome organization, gene structure, and expression and DNA replication.
[
BIOC 3400
]
Understand autophagy.
[
BIOC 4305
]
Distinguish the differences in DNA packaging/chromatin organization between prokaryotes and eukaryotes.
[
BIOC 3400
]
Provide evidence for the roles of catalytic RNA in different cellular process such as protein synthesis and RNA splicing
[
BIOC 3400
]
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